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©The Author(s) 2020.
World J Clin Cases. Nov 6, 2020; 8(21): 5104-5115
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5104
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5104
Table 2 Univariate and multivariate Cox regression analyses for predicting oncological outcomes in patients treated with radical nephroureterectomy for upper urinary tract urothelial carcinoma
Variable | IRFS | CSS | OS | |||||||||||||||
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||||||||||
HR | 95%CI | P value | HR | 95%CI | P value | HR | 95%CI | P value | HR | 95%CI | P value | HR | 95%CI | P value | HR | 95%CI | P value | |
Age < 70 yr vs age ≥ 70 yr | 0.799 | 0.412-1.550 | 0.507 | - | 0.968 | 0.398-2.353 | 0.943 | 1.340 | 0.656-2.737 | 0.421 | ||||||||
Male vs female | 0.535 | 0.273-1.047 | 0.068 | - | 0.820 | 0.339-1.986 | 0.661 | 0.644 | 0.315-1.319 | 0.229 | ||||||||
BCE methods | 0.987 | - | 0.826 | 0.503 | ||||||||||||||
IVBC | 1 | Reference | - | - | 1 | Reference | - | 1 | Reference | - | ||||||||
EVBC | 1.032 | 0.474-2.246 | 0.937 | 0.707 | 0.235-2.128 | 0.537 | 0.587 | 0.223-1.542 | 0.280 | |||||||||
TUBC | 0.954 | 0.392-2.323 | 0.917 | 0.879 | 0.276-2.797 | 0.828 | 0.695 | 0.256-1.884 | 0.474 | |||||||||
Tumor location | 0.042 | 0.042 | 0.564 | 0.161 | ||||||||||||||
Lower ureter | 1 | Reference | - | 1 | Reference | - | 1 | Reference | - | 1 | Reference | - | ||||||
Middle and upper ureter | 0.421 | 0.177-1.002 | 0.051 | 0.421 | 0.177-1.002 | 0.051 | 0.930 | 0.295-2.933 | 0.901 | 1.148 | 0.451-2.920 | 0.772 | ||||||
Renal pelvis or calyx | 0.339 | 0.153-0.750 | 0.008 | 0.339 | 0.153-0.750 | 0.008 | 0.505 | 0.160-1.598 | 0.245 | 0.466 | 0.176-1.230 | 0.123 | ||||||
Multiple | 0.315 | 0.007-1.416 | 0.132 | 0.315 | 0.007-1.416 | 0.132 | 0.459 | 0.053-3.973 | 0.479 | 0.500 | 0.102-2.462 | 0.394 | ||||||
pT ≤ 2 vs pT > 2 | 0.567 | 0.273-1.178 | 0.128 | 9.156 | 2.673-31.358 | 0.000 | 8.439 | 2.424-29.377 | 0.001 | 2.970 | 1.417-6.225 | 0.004 | 2.891 | 1.364-6.128 | 0.006 | |||
LN (-/x) vs LN (+) | 0.901 | 0.123-6.586 | 0.918 | 16.793 | 6.328-44.568 | 0.000 | 14.343 | 5.176-39.745 | < 0.001 | 9.917 | 3.995-24.621 | 0.000 | 9.473 | 3.75-23.926 | < 0.001 | |||
Tumor grade | 0.988 | 0.383-2.547 | 0.980 | 25.367 | 0.083-7755.852 | 0.268 | 0.981 | 0.341-2.826 | 0.972 | |||||||||
LV (-) vs LV (+) | 0.611 | 0.146-2.552 | 0.499 | 2.933 | 0.969-8.881 | 0.057 | 2.385 | 0.907-6.273 | 0.078 | |||||||||
Urinary cytology | 0.993 | 0.478-2.064 | 0.986 | 1.474 | 0.492-4.419 | 0.488 | 1.446 | 0.592-3.532 | 0.418 | |||||||||
Intravesical chemotherapy (yes vs no) | 1.023 | 0.503-2.081 | 0.950 | 0.606 | 0.202-1.816 | 0.371 | 0.852 | 0.380-1.909 | 0.697 |
- Citation: Lai SC, Wu PJ, Liu JY, Seery S, Liu SJ, Long XB, Liu M, Wang JY. Oncological impact of different distal ureter managements during radical nephroureterectomy for primary upper urinary tract urothelial carcinoma. World J Clin Cases 2020; 8(21): 5104-5115
- URL: https://www.wjgnet.com/2307-8960/full/v8/i21/5104.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v8.i21.5104