Malignant tumors associated with Peutz-Jeghers syndrome: Five cases from a single surgical unit

Figure 2 Intraoperative exploration, pathological specimens, and postoperative pathological features of case 1. A: Small intestinal intussusceptions during intraoperative exploration; B: Liver metastasis observed during intraoperative exploration; C: Total stomach tissue, multiple polyps in the small intestine, intra-hepatic metastatic nodules, and pathological materials; D: P-J polyps (H&E staining; magnification, × 10); E: Carcinomas invading the intrinsic myometrium (H&E staining; magnification, × 50); F: Highly differentiated adenocarcinoma (H&E staining; magnification, × 200); G: Adenocarcinoma infiltration in the liver tissue (H&E staining; magnification, × 100); H: Sanger sequencing (forward and backward) revealed a heterozygous deletion, c.471_472delCT; I: Gene structure of STK11 with a mutation in exon 4.