Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients

Table 1 Baseline characteristics of patients enrolled

Characteristics	Total, n = 213	Survival, n = 178	Death, n = 35	P value, death vs survival
Age in yr, median (IQR)	62 (51-69)	60 (49-67)	73 (65-84)	< 0.001
Sex
Male	95 (44.6%)	71 (39.9%)	24 (68.6%)	0.002
Comorbidities
Hypertension	59 (27.7%)	44 (24.7%)	15 (42.8%)	0.028
Diabetes	22 (10.3%)	18 (10.1%)	4 (11.4%)	0.815
Cardiovascular disease	17 (8.0%)	12 (6.7%)	5 (14.3%)	0.132
Cerebrovascular disease	10 (4.7%)	4 (2.2%)	6 (17.1%)	< 0.001
Chronic kidney disease	9 (4.2%)	5 (2.8%)	4 (11.4%)	0.02
COPD	10 (4.7%)	4 (2.2%)	6 (17.1%)	< 0.001
Malignancy	10 (4.7%)	8 (4.5%)	2 (5.7%)	0.755
Autoimmune disease	4 (1.9%)	3 (1.7%)	1 (2.9%)	0.641
Vital signs at admission
Heart rate as bpm, median (IQR)	85 (78-92)	84 (76-91)	86 (79-95)	0.198
SBP in mmHg, median (IQR)	125 (116-135)	125 (118-134)	124 (110-143)	0.535
DBP in mmHg, median (IQR)	76 (70-80)	77 (70-80)	74 (65-86)	0.683
Respiration rate times per min, median (IQR)	20 (18-21)	19 (18-20)	23 (19-27)	< 0.001
Spectrum
Moderate	83 (39.0%)	83 (46.6%)	0
Severe	79 (37.1%)	79 (44.4%)	0
Critical	51 (23.9%)	16 (9.0%)	35 (100.0%)
Symptom onset to admission/d, median (IQR)	10 (7-12)	10 (7-12)	10 (7-14)	0.453
Hospitalization stay in d, median (IQR)	27 (14-35)	32 (22-36)	6 (4-8)	< 0.001

BPM: Beats per min; COPD: Chronic obstructive pulmonary disease; DBP: Diastolic blood pressure; IQR: Interquartile range; SBP: Systolic blood pressure.