Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis

doi:10.12998/wjcc.v8.i19.4320

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 6, 2020; 8(19): 4320-4330
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4320

Table 4 Impact of interactions between genotypes of mTOR gene and tea drinking on incidence of tuberculosis

		Tea drinking		RERI_c	RERI_a¹ (95%CI)
		No	Yes
rs2295080	TT	245	364	-2.0341	-1.5187 (-1.9826, -1.0547)^a
rs2295080	GT + GG	212	176	-2.0341	-1.5187 (-1.9826, -1.0547)^a
rs2024627	CC	367	468	-1.6561	-1.8270 (-2.3587, -1.2952)^a
rs2024627	CT + TT	90	72	-1.6561	-1.8270 (-2.3587, -1.2952)^a
rs1057079	TT	228	373	-2.7054	-2.3246 (-2.9417, -1.7076)^a
rs1057079	CT + CC	229	167	-2.7054	-2.3246 (-2.9417, -1.7076)^a
rs7525957	TT	326	444	-1.3684	-0.4235 (-0.7756, -0.0714)^a
rs7525957	CT + CC	131	96	-1.3684	-0.4235 (-0.7756, -0.0714)^a

¹Adjusted for the covariates of sex, age, marital status, educational background, body mass index, smoking status, alcohol drinking and Bacillus Calmette–Guérin vaccination.

^aP < 0.05, RERI < 0 suggests negative interactions. RERI: Relative excess risk of interaction.

Citation: Wang M, Ma SJ, Wu XY, Zhang X, Abesig J, Xiao ZH, Huang X, Yan HP, Wang J, Chen MS, Tan HZ. Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis. World J Clin Cases 2020; 8(19): 4320-4330
URL: https://www.wjgnet.com/2307-8960/full/v8/i19/4320.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i19.4320