Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis

Table 1 Demographic characteristics and associated risk factors in tuberculosis patients vs. healthy controls

	TB patients (n = 503)		Healthy controls (n = 494)		χ2	P value
	n	%	n	%
Sex
Male	369	73.36	348	70.45	1.048	0.306
Female	134	26.64	146	29.55
Age, yr
18-30	68	13.52	78	15.79	1.908	0.592
31-50	190	37.77	178	36.03
51-70	167	32.20	153	30.97
> 70	78	15.51	85	17.21
Marital status
Married	345	68.59	330	66.80	0.364	0.546
Other	158	31.41	164	33.20
Educational background
Primary school or below	198	39.36	220	44.53	2.824	0.244
Junior high school	161	32.01	148	29.96
Senior high school or above	144	28.63	126	25.51
BMI, kg/m2
< 18.5	180	35.79	169	34.21	9.310	0.010a
18.5-24.9	297	59.05	274	55.47
≥ 25.0	26	5.17	51	10.32
History of BCG vaccination
Yes	105	20.87	141	28.54	7.884	0.005a
No	398	79.13	353	71.46
Smoking
Yes	298	59.24	240	48.58	11.403	< 0.001a
No	205	40.76	254	51.42
Alcohol drinking
Yes	91	18.09	77	15.59	1.116	0.291
No	412	81.91	417	84.41
Tea drinking
Yes	247	49.11	293	59.31	10.457	0.001a
No	256	50.89	201	40.69

^aP < 0.05. TB: Tuberculosis; BMI: Body mass index; BCG: Bacillus Calmette–Guérin.