Role of monoclonal antibody drugs in the treatment of COVID-19

doi:10.12998/wjcc.v8.i19.4280

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Oct 6, 2020 (publication date) through Nov 3, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 6, 2020; 8(19): 4280-4285
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4280

Table 1 Randomized clinical trials ongoing on promising inflammatory strategy

Target	Drug type	Drugs
IL 6 signaling	Anti-IL 6	Clazakizumab, Siltuximab
IL 6 signaling	Anti-IL6 receptor	Sarilumab, Tocilizumab
IL 1 signaling	Anti-IL1β	Canakinumab
IL 1 signaling	Anti-IL1 repector	Anakinra
JAK-STAT signaling	JAK1/JAK2 inhibitors	Baricitinib, Ruxolitinib
	JAK1/JAK3 inhibitors	Tofacitinib

JAK-STAT: The Janus kinase/signal transducer and activator of tran-ions; IL: Interleukin.

Citation: Ucciferri C, Vecchiet J, Falasca K. Role of monoclonal antibody drugs in the treatment of COVID-19. World J Clin Cases 2020; 8(19): 4280-4285
URL: https://www.wjgnet.com/2307-8960/full/v8/i19/4280.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i19.4280