Celiac disease and Sjögren’s syndrome: A case report and review of literature

Table 1 Summary of studies reporting prevalence of celiac disease in Sjogren syndrome

Ref.	SS (n)	Country	CD prevalence (SS + CD)	Serological criteria	Histological criteria
Iltanen et al[16]	34 SS+, 28 controls	Finland	14.7% (n = 5)	SS+ CD; 3/5 IgA EMA+; 4/5 IgA AGA+; 5/5 IgA EMA or AGA +; SS – CD; 0/28 IgA EMA +; 9/28 IgA AGA +	All 5 seropositive - Marsh 3
Szodoray et al[17]	111 SS+	Hungary	4.5% (n =5 )	6/111 tTG and/or AGA and/or EMA +	5/6 CD+, one with jejunitis
Bartoloni et al[18]	354 SS+, 14298 controls	Italy	7.1% (n = 25), 6.8% (n = 24) previously diagnosed CD, 1 latent CD	24 previously diagnosed (2013 WGO guideline criteria), 1 IgA tTG+	All 25
Bizzaro et al[19]	100 SS+	Italy, Israel	1% (n = 1)	1 IgG tTG + (IgA tTG-)	Histology not done
Luft et al[20]	50 SS+, 50 controls 40 disease-controls (CD+)	Canada	12% (n = 6)	6 IgA tTG +	5/6 biopsy-proven CD
Caio et al[21]	52 SS+	Italy	5.8% (n = 3)	3/42 IgA tTG+, IgG DGP + and IgA EMA+	Histology not used

SS: Sjogren syndrome; CD: Celiac disease; AGA: Anti-gliadin antibodies; EMA: Antiendomysial antibodies.