Shear wave elastography may be sensitive and more precise than transient elastography in predicting significant fibrosis

Table 2 Performance characteristics of shear wave elastography and transient elastography for staging liver fibrosis in chronic hepatitis B patients

Parameters	AUROC	Cutoff Value (kPa)	Sensitivity, %	Specificity, %	PPV, %	NPV, %	LR+	LR-
SWE	0.786	9.05	77.78	77.78	77.78	77.78	3.50	0.29
TE	0.714	8.15	59.26	66.67	64.00	62.07	1.78	0.61
FIB-4	0.551	0.91	74.07	44.44	57.14	63.16	1.33	0.58
APRI	0.556	0.37	81.48	44.44	59.46	70.59	1.47	0.42

Characteristics are based on optimal cutoff elasticity values. Pathologic analysis was the diagnostic reference standard. PPV: Positive predictive value; NPV: Negative predictive value; LR+: Positive likelihood value; LR-: Negative likelihood value; SWE: Shear wave elastography; TE: Transient elastography; FIB-4: Fibrosis-4; APRI: Aspartate aminotransferase to platelet ratio index.