Comparison of gemcitabine plus nab-paclitaxel and FOLFIRINOX in metastatic pancreatic cancer

doi:10.12998/wjcc.v8.i17.3718

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Sep 6, 2020; 8(17): 3718-3729
Published online Sep 6, 2020. doi: 10.12998/wjcc.v8.i17.3718

Table 6 Adverse events of each regimen

Adverse events	GA (n = 54), n (%)	FOLFIRINOX (n = 47), n (%)	P value
Admission	18 (33.3)	18 (38.3)	0.608
Thromboembolism	3 (5.6)	9 (19.1)	0.035^a
Neuropathy (Grade 1,2/3,4)	28 (51.9) (11/17)	11 (23.4) (10/1)	0.000^b
Neutropenia (Grade 1,2/3,4)	38 (70.4) (12/26)	35 (74.5) (10/25)	0.496
Thrombocytopenia (Grade 1,2/3,4)	22 (40.7) (13/9)	17 (36.2) (6/11)	0.893
Nausea (Grade 1,2/3,4)	11 (20.4) (9/2)	22 (46.8) (18/4)	0.008^b
Fatigue (Grade 1,2/3,4)	31 (57.4) (19/12)	26 (55.3) (17/9)	0.740
Diarrhea (Grade 1,2/3,4)	10 (18.5) (7/3)	12 (25.5) (7/5)	0.322
Colitis/pneumonia	11 (20.4) (4/7)	13 (27.7) (7/6)	0.616

^aP < 0.05,

^bP < 0.01. GA: Gemcitabine plus nab-paclitaxel.

Citation: Han SY, Kim DU, Seol YM, Kim S, Lee NK, Hong SB, Seo HI. Comparison of gemcitabine plus nab-paclitaxel and FOLFIRINOX in metastatic pancreatic cancer. World J Clin Cases 2020; 8(17): 3718-3729
URL: https://www.wjgnet.com/2307-8960/full/v8/i17/3718.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i17.3718