Comparison of gemcitabine plus nab-paclitaxel and FOLFIRINOX in metastatic pancreatic cancer

doi:10.12998/wjcc.v8.i17.3718

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Sep 6, 2020; 8(17): 3718-3729
Published online Sep 6, 2020. doi: 10.12998/wjcc.v8.i17.3718

Table 5 Result in subgroup analysis (Eastern Cooperative Oncology Group)

	ECOG = 0 (n = 52)			ECOG = 1 (n = 43)			ECOG = 2 (n = 6)			P value
	GA (n = 25)	FFX (n = 27)	P value	GA (n = 23)	FFX (n = 20)	P value	GA (n = 6)	FFX (n = 0)	P value	P value
PFS (mo)	6.60 (4.28-8.92)			3.90 (2.46-5.34)			3.27 (0.00-8.12)			0.003^b
PFS (mo)	8.93 (4.64-13.22)	5.43 (4.58-6.28)	0.002^b	3.87 (2.03-5.71)	4.40 (1.84-6.96)	0.511	3.27 (0.00-8.12)	NA	NA
OS (mo)	10.77 (6.26-15.28)			6.27 (4.26-8.28)			4.47 (0.00-14.00)			0.000^b
OS (mo)	16.10 (10.50-21.70)	6.97 (3.53-10.41)	0.000^b	6.10 (3.31-8.89)	6.27 (2.76-9.78)	0.674	4.47 (0.00-14.00)	NA	NA

^bP < 0.01, mean ± SD. NA: Not-availiable; ECOG: Eastern Cooperative Oncology Group; PFS: Progression free survival; OS: Overall survival; GA: Gemcitabine plus nab-paclitaxel; FFX: FOLFIRINOX.

Citation: Han SY, Kim DU, Seol YM, Kim S, Lee NK, Hong SB, Seo HI. Comparison of gemcitabine plus nab-paclitaxel and FOLFIRINOX in metastatic pancreatic cancer. World J Clin Cases 2020; 8(17): 3718-3729
URL: https://www.wjgnet.com/2307-8960/full/v8/i17/3718.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i17.3718