Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis of Helicobacter pylori gastritis, precancerous gastric lesion, and neoplasia

Table 3 Determination of the horizontal extent of early gastric cancer by magnifying narrow-band imaging

Ref.	Study design	Lesion (n)	Pathology	Diagnostic accuracy	P value
Kiyotoki et al[61]	Comparative study between CE and M-NBI	EGC (70), adenoma (13)	ESD	77.8% vs 97.4%	0.009
	Marking dots were placed on the tumor margins
Nagahama et al[63]	M-NBI for unclear margins by CE	EGC (350)	ESD	81.1% → 94.8%	< 0.001
Uchita et al[64]	Combination of CE and M-NBI	EGC (161)	ESD	72.7% → 98.1%	< 0.001
Asada-Hirayama et al[62]	Comparative study between CE and M-NBI	EGC (109)	ESD	75.9% vs 89.4%	0.007
	Oral and anal tumor margins of the same lesion
Nagahama et al[66]	Comparative study between CE and M-NBI	EGC (343)	Biopsy	85.7% vs 88.0%	0.63
	Biopsies outside and inside the tumor margins
Horii et al[65]	Non-comparative study using M-NBI only	EGC (330)	Biopsy, ESD	96.7%-97.9%	N/A

CE: Chromoendoscopy; M-NBI: Magnifying narrow-band imaging; EGC: Early gastric cancer; ESD: Endoscopic submucosal dissection; N/A: Not applicable.