Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis of Helicobacter pylori gastritis, precancerous gastric lesion, and neoplasia

Table 2 Diagnostic performance of narrow-band imaging with magnification for early gastric cancer

Ref.	Year	Endoscopic criteria of NBI with magnification	NBI with magnification (vs white light imaging)
			Sensitivity	Specificity	Accuracy
Yao et al[52]	2007	Irregular microvascular pattern	92.9%	99.3%	98.7%
Ezoe et al[53]	2010	Demarcation line	70.0% (33.3%1)	88.8% (66.6%1)	78.9% (43.8%1)
		Irregular microvascular pattern
Kato et al[58]	2010	Disappearance of fine mucosal structure	92.9% (42.9%)	94.7% (61.0%)	N/A
		Microvascular dilation
		Microvascular heterogeneity in shape
Yamada et al[54]	2014	Demarcation line	95% (40%2)	97% (68%2)	97% (65%2)
		Irregular microvascular pattern
Yao et al[56]	2014	VS classification	85.7%	99.4%	98.1%
Fugiwara et al[57]	2015	VS classification	78.0% (43.7%3)	92.9% (81.6%3)	88.3% (69.9%3)
Kanesaka et al[59]	2015	Microvascular dilation	25%	90%	83%
		Microvascular tortuosity	55%	24%	28%
		Difference in caliber	13%	99%	89%
		Variation in shape	70%	95%	92%

¹Diagnostic sensitivity, specificity, and accuracy using white-light endoscopy with magnification.

²Endoscopic criteria of white-light endoscopy for gastric cancer were an irregular margin and a spiny depressed area.

³Diagnostic sensitivity, specificity, and accuracy using chromoendoscopy with indigo carmine. NBI: Narrow-band imaging; VS: Vessel plus surface; N/A: Not applicable.