Elevated serum growth differentiation factor 15 in multiple system atrophy patients: A case control study

Table 3 Receiver-operating characteristic curve analysis of serum growth differentiation factor 15 levels as a potential multiple system atrophy diagnostic biomarker

Group	Subtype	AUC	SE	95%CI	P value	Cutoff, pg/mL	Sensitivity, %	Specificity, %
MSA vs Control	Overall	0.929	0.027	0.876-0.981	0.000	470.42	85.7	88.0
	Male	0.954	0.030	0.896-1.000	0.000	552.10	82.6	100.0
	Female	0.905	0.044	0.820-0.990	0.000	470.42	80.8	90.0
MSA vs PD	Overall	0.765	0.048	0.671-0.859	0.000	1075.91	51.0	96.0
	Male	0.772	0.072	0.630-0.914	0.001	1075.91	65.2	95.8
	Female	0.783	0.066	0.654-0.911	0.000	616.39	65.4	88.5

MSA: Multiple system atrophy; PD: Parkinson disease; AUC: Area under the receiver-operating characteristic curve.