Elevated serum growth differentiation factor 15 in multiple system atrophy patients: A case control study

doi:10.12998/wjcc.v8.i12.2473

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Clin Cases. Jun 26, 2020; 8(12): 2473-2483
Published online Jun 26, 2020. doi: 10.12998/wjcc.v8.i12.2473

Table 1 Clinical characteristics of multiple system atrophy patients, Parkinson disease patients and controls

	MSA	PD	Control	P value
All
Subjects, n	49	50	50	-
Age, yr	61.7 ± 7.7	61.4 ± 7.5	58.5 ± 7.5	0.077
Female/male, n	26/23	26/24	30/20	0.683
Age of onset, yr	58.7 ± 7.4	56.6 ± 7.1	-
MSA-P/MSA-C, n	30/20	-	-	-
Probable/Possible, n	31/18	-	-	-
Clinical rate scales (UMSARSII/UPDRSIII)	19.5 ± 6.4 (UMSARSII)	26.1 ± 13.2 (UPDRSIII)	- -	-
GDF15, pg/mL	1105.69 (984.24)	506.70 (346.80)	313.85 (247.76)	0.000

MSA: Multiple system atrophy; MSA-P: Multiple system atrophy-parkinsonian type; MSA-C: Multiple system atrophy-cerebellar type; PD: Parkinson disease; GDF15: Growth differentiation factor 15.

Citation: Yue T, Lu H, Yao XM, Du X, Wang LL, Guo DD, Liu YM. Elevated serum growth differentiation factor 15 in multiple system atrophy patients: A case control study. World J Clin Cases 2020; 8(12): 2473-2483
URL: https://www.wjgnet.com/2307-8960/full/v8/i12/2473.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i12.2473