Role of IL-17 gene polymorphisms in osteoarthritis: A meta-analysis based on observational studies

Table 2 Genotype distributions of IL-17 gene polymorphisms in the included studies

Ref.	Source of control	Ethnicity	Allele		Case			Control			Association with osteoarthritis
			1	0	11	10	00	11	10	00
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Zhang et al[20], 2019	HB	Asian	G	A	42	53	27	49	63	12	AA genotype/A allele increased OA risk
Zhang et al[20], 2019	HB	Asian			23	32	21	26	28	14	Not related
Jiang et al[21], 2019	HB	Asian			204	170	34	289	194	23	AA genotype/A allele increased OA risk
Bai et al[22], 2019	HB	Asian			189	271	134	207	265	104	AA genotype/A allele increased OA risk
Bafrani et al[12], 2019	HB	Caucasians			83	35	9	69	51	7	GA genotype decreased OA risk
Vrgoc et al[23], 2018	HB	Caucasians			78	71	23	190	172	45	Not related
Vrgoc et al[23], 2018	HB	Caucasians			76	85	25	190	172	45	Not related
Han et al[24], 2014	HB	Asian			52	109	141	97	106	97	GG genotype decreased OA risk
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Zhang et al[20], 2019	HB	Asian	T	C	91	30	1	98	24	2	Not related
Zhang et al[20], 2019	HB	Asian			59	16	1	54	13	1	Not related
Jiang et al[21], 2019	HB	Asian			356	49	4	423	80	2	Not related
Bai et al[22], 2019	HB	Asian			380	188	26	411	155	10	CC/TC genotype/C allele increased OA risk
Bafrani et al[12], 2019	HB	Caucasians			98	26	3	112	13	2	TC genotype/C allele increased OA risk
Vrgoc et al[23], 2018	HB	Caucasians			198	34	0	493	34	1	C allele increased OA risk
Vrgoc et al[23], 2018	HB	Caucasians			195	14	1	493	34	1	Not related
Han et al[24], 2014	HB	Asian			226	59	17	236	56	8	Not related
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Bafrani et al[12], 2019	HB	Caucasians	T	C	111	16	0	109	18	0	Not related
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Vrgoc et al[23], 2018	HB	Caucasians	G	A	57	129	58	49	91	46	Not related
Vrgoc et al[23], 2018	HB	Caucasians			68	111	51	49	91	46	Not related

HB: Hospital-based; OA: Osteoarthritis.