Evaluation of clinical significance of claudin 7 and construction of prognostic grading system for stage II colorectal cancer

doi:10.12998/wjcc.v8.i11.2190

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jun 6, 2020; 8(11): 2190-2200
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2190

Table 4 Prognostic stratification analysis based on different grades

Variable	HR	95%CI	P value
Grade A (claudin 7-high and PNI-)	1	-	-
Grade B (claudin 7-high and PNI+, claudin 7-low and PNI-)	2.512	1.084-5.817	0.032
Grade C (claudin 7-low and PNI+)	7.963	2.704-23.452	< 0.001

Grade C vs Grade B, P = 0.040 (HR = 2.987; 95%CI: 1.051-8.489). HR: Hazard ratio. Claudin 7-high: Claudin 7 high expression; claudin 7-low: Claudin 7 low expression; PNI-: Perineural invasion negative; PNI+: Perineural invasion positive. CI: Confidence interval; HR: Hazard ratio.

Citation: Quan JC, Peng J, Guan X, Liu Z, Jiang Z, Chen HP, Zhuang M, Wang S, Sun P, Wang HY, Zou SM, Wang XS. Evaluation of clinical significance of claudin 7 and construction of prognostic grading system for stage II colorectal cancer. World J Clin Cases 2020; 8(11): 2190-2200
URL: https://www.wjgnet.com/2307-8960/full/v8/i11/2190.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i11.2190