Cytapheresis for pyoderma gangrenosum associated with inflammatory bowel disease: A review of current status

Table 1 Clinical characteristics of cases treated with cytapheresis

Case (number)	Ref.	First authors	Reporting year	Age (yr)	Gender	The site of PG	Associated disease	Treatment before apheresis
1	[8]	Ohmori T	2003	19	M	Buttocks and legs	CD	5-ASA
2	[14]	Ishikawa H	2004	30	M	Abdomen, right iliac	UC	GC, CsA
3	[15]	Murata M	2004	31	M	Right lower leg	UC	GC
4	[16]	Yoneda K	2005	39	F	Face and head	UC	GC
5	[17]	Yanar-Fujisawa R	2005	31	F	Left ankle and right knee	UC	GC
6	[20]	Seishima M	2007	29	F	Lower bilateral legs	UC	GC, SASP
7	[21]	Fujino Y	2008	55	F	Lower bilateral legs	UC	GC, 5-ASA
8	[22]	Kawakami T	2009	19	M	Head	UC	GC, SASP
9	[23]	Doi R	2010	19	M	Forehead	UC	GC, SASP
10	[24]	Kobayashi S	2011	29	M	Right lower leg	UC	GC, SASP
11	[25]	Ikeda K	2011	36	F	Lower leg, neck and upper trunk	UC	GC
12	[26]	Uchiyama K	2011	50	F	Lower limbs	UC	GC
13	[27]	Urushibara M	2014	44	F	Back, left leg	UC	GC, 5-ASA, FK506
14	[28]	Izaki S	2014	49	F	Forearms	UC	SASP, PI
15	[29]	Ohno M	2016	36	F	Lower limbs	UC	SASP
16	[31]	Okada M	2017	71	F	Buttocks	UC	GC, 5-ASA
17	[32]	Yamashita A	2017	30	F	Top of the foot	UC	5-ASA
18	NA	Our Case	2018	57	M	Left lower leg	UC	GC, 5-ASA
19	[33]	Murata M	2003	19	F	Lower left leg	UC	GC
20	[34]	Fujimoto E	2004	42	M	Legs	UC	GC, SASP
21	[35]	Watanabe Y	2008	60	F	Left dorsal femur	UC	GC, DDS, CsA
22	[36]	Hanafusa T	2011	73	F	Sternum and chest	IBD, breast cancer	GC, DDS, CsA
23	[37]	Ito A	2015	43	F	Lower left leg	UC	GC, SASP

M: Male; F: Female; IBD: Inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis; RA: rheumatoid arthritis; MDS: Myelodysplastic syndromes; GC: Glucocorticoid; SASP: Salazosulfapyridine; 5-ASA: 5-aminosalicylic acid; CsA: Cyclosporine; PI, potassium iodide; DDS: Diamino diphenyl sulfone; NA: Not available.