Early-onset refractory diarrhea due to immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome associated with a novel mutation in the FOXP3 gene: A case report

Figure 4 Schematic representation of the FOXP3 gene and protein. Numbers along the top line indicate amino acid number (1–431). The latter two lines refer to the gene structure, the coding and non-coding regions: N-terminal domain (orange), zinc-finger (ZF) domain (green), leucine-zipper (LZ) domain (blue), LZ-FKH loop (yellow), and FKH domain (red). The orange arrows indicate the mutation site identified in this study.