Ligliptin for treatment of type 2 diabetes mellitus with early renal injury: Efficacy and impact on endogenous hydrogen sulfide and endothelial function

doi:10.12998/wjcc.v8.i10.1878

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 26, 2020; 8(10): 1878-1886
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1878

Table 4 Comparison of serum endogenous hydrogen sulfide and endothelial cell particles before and after treatment between the two groups

	Ligliptin treatment group	Gliquidone treatment group	P value
Number of cases	54	56
H₂S (μmol/L)
Before treatment	73.39 (9.28)	75.58 (10.16)	0.241
After treatment	40.04 (8.82)^a	56.12 (9.90)^a	0.000
Endothelial cell granules
Before treatment	1459.28 (210.22)	1430.04 (201.78)	0.458
After treatment	133.40 (34.39)^a	202.32 (50.43)^a	0.000

^aP < 0.05 vs before treatment. H₂S: Hydrogen sulfide.

Citation: Zhang J, Du YL, Zhang H, Sui H, Hou WK. Ligliptin for treatment of type 2 diabetes mellitus with early renal injury: Efficacy and impact on endogenous hydrogen sulfide and endothelial function. World J Clin Cases 2020; 8(10): 1878-1886
URL: https://www.wjgnet.com/2307-8960/full/v8/i10/1878.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i10.1878