Ligliptin for treatment of type 2 diabetes mellitus with early renal injury: Efficacy and impact on endogenous hydrogen sulfide and endothelial function

doi:10.12998/wjcc.v8.i10.1878

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 26, 2020; 8(10): 1878-1886
Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.1878

Table 3 Comparison of renal function indexes between the two groups before and after treatment

	Ligliptin treatment group	Gliquidone treatment group	P value
Number of cases	54	56
UAER (μg/min)
Before treatment	110.21 (18.82)	107.82 (20.11)	0.522
After treatment	70.32 (11.21)^a	88.42 (12.27)^a	0.000
BUN (mmol/L)
Before treatment	6.10 (1.12)	6.05 (1.09)	0.813
After treatment	5.77 (1.04)^a	5.79 (1.21)^a	0.926
Cr (μmol/L)
Before treatment	110.38 (15.56)	108.82 (18.81)	0.637
After treatment	108.02 (12.38)	107.22 (11.87)	0.730
CysC (mg/L)
Before treatment	1.74 (0.30)	1.78 (0.33)	0.508
After treatment	1.65 (0.33)^a	1.67 (0.35)^a	0.759

^aP < 0.05 vs before treatment. UAER: Urinary albumin excretion rate; BUN: Blood urea nitrogen; Cr: Creatinine; CysC: Cystatin C.

Citation: Zhang J, Du YL, Zhang H, Sui H, Hou WK. Ligliptin for treatment of type 2 diabetes mellitus with early renal injury: Efficacy and impact on endogenous hydrogen sulfide and endothelial function. World J Clin Cases 2020; 8(10): 1878-1886
URL: https://www.wjgnet.com/2307-8960/full/v8/i10/1878.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i10.1878