Oncogenic role of Tc17 cells in cervical cancer development

Figure 4 Tc17 cell-derived interleukin-17 induces tumor cells to produce CXCL12. A: Primary tumor cells were cultured with various concentrations of interleukin (IL)-17, IL-22, interferon-γ, and the production of CXC12 was detected in the culture supernatants by ELISA and statistically analyzed; B: Primary tumor cells were cultured with various concentrations of cytokines or monocyte-derived Tc17 cells culture supernatants, and the production of CXC12 was detected in the culture supernatants by ELISA and statistically analyzed. Comparisons were performed using the t-test. ^aP < 0.05; ^bP < 0.01. Error bars represent SE. NS: No significant difference; NM: Non-tumor tissue monocyte-derived; BM: Blood monocyte-derived; TAMs: Tumor tissue monocyte-derived.