Six families with balanced chromosome translocation associated with reproductive risks in Hainan Province: Case reports and review of the literature

Table 2 Chromosome detection rates in China’s 20 provinces and cities and 16 countries

No	Region	Anomaly chromosome detection rate	Incidence of autosomal balanced translocation	Medical history
1	Hainan Province, China[21]	10.5% (353/3353)	0.44% (15/3353)	Genetic counselors
2	Gansu Province, China[22]	3.91% (51/1304)	1% (13/1304)	Genetic counselors
3	Ningxia Hui Autonomous Region, China[23]	3.52% (36/1024)	2.5% (26/1024)	Recurrent spontaneous abortion
4	Shanxi Province, China[24]	23.76% (307/1292)	14% (185/1292)	Abnormal child-bearing history
5	Shandong Province, China[25]	4.73% (309/6534)	0.39% (26/6534)	Abnormal child-bearing history
6	Hebei Province, China[26]	2.09% (70/3348)	1.1% (36/3348)	Infertility
7	Zhejiang Province, China[27]	6.6% (106/1601)	0.5% (8/1601)	Infertility
8	Shanghai, China[28]	3.96% (111/2798)	1.24% (37/2798)	Natural abortion
9	Fujian Province, China[29]	4.32% (87/2110)	1.18% (25/2110)	Abnormal child-bearing history
10	Beijing, China[30]	7 % (28/400)	2.5% (10/400)	Abnormal child-bearing history
11	Anhui Province, China[31]	5.35% (353/6600)	2.98% (197/6600)	Infertility
12	Hubei Province, China[32]	20.2% (315/1559)	3.72% (58/1559)	Recurrent abortion
13	Guizhou Province, China[33]	5.12% (32/625)	4.16% (26/625)	Abnormal child-bearing history
14	Yunnan Province, China[34]	1.5% (3/200)	1% (2/200)	Abnormal child-bearing history
15	Guangdong Province, China[35]	10.37% (132/1273)	1.1% (14/1273)	Abnormal child-bearing history
16	Jiangsu Province, China[36]	1.7% (90/5292)	0.6% (32/5292)	Infertility
17	Hunan Province, China[37]	3.14% (111/3540)	1.67% (59/3540)	Natural abortion
18	Heilongjiang Province, China[38]	4.51% (82/455)	3.3% (15/455)	Genetic counselors
19	Henan Province, China[39]	11.5% (21/182)	4.4% (8/182)	Natural abortion
20	Sichuan Province, China[40]	4% (106/2643)	0.45% (12/2643)	Genetic counselors
21	Republic of Macedonia[41]	0.47% (16/3800)	0.21% (8/3800)	Natural abortion
22	United Kingdom of Great Britain and Northern Ireland[42]	3.52% (56/1590)	2.26% (36/1590)	Recurrent abortion
23	Turkey[43]	4.1% (124/3020)	0.99% (30/3020)	Natural abortion
24	Republic of India[44]	6.8% (54/788)	5.9% (47/788)	Recurrent abortion
25	Japan[45]	4.3% (55/1278)	1.5% (19/1278)	Recurrent abortion
26	Morocco[46]	11% (137/1254)	2.71% (34/1254)	Recurrent abortion
27	Islamic Republic of Iran[47]	11.7% (170/1456)	7.35% (107/1456)	Recurrent abortion
28	the United Mexican States[48]	7.6% (24/316)	1.27% (4/316)	Recurrent abortion
29	Sultanate of Oman[49]	3.42% (26/760)	2.8% (21/760)	Recurrent abortion
30	Kingdom of Saudi Arabia[50]	7.2% (154/2148)	3.35% (72/2148)	Recurrent abortion
31	Magyarország[51]	3.39% (8/236)	0.85% (2/236)	Recurrent abortion
32	Islamic Republic of Pakistan[52]	5.3% (32/600)	2.3% (14/600)	Recurrent abortion
33	The Republic Of Poland[53]	6.2% (16/258)	4.65% (12/258)	Recurrent abortion
34	Russia[54]	2.37% (81/3414)	1.9% (65/3414)	Infertility
35	Tunis[55]	8.5% (28/326)	3.68% (12/326)	Recurrent abortion
36	Spain[56]	17.7% (158/890)	4.27% (38/890)	Recurrent abortion
Total (1-20)		5.86% (2703/46133)	1.74% (804/46133)
Total (21-36)		5.15% (1139/22134)	2.35% (521/22134)
Total (1-36)		5.62% (3842/68267)	1.97% (1325/68267)