Six families with balanced chromosome translocation associated with reproductive risks in Hainan Province: Case reports and review of the literature

Table 1 History comparison table of the six families

Items	Family 1	Family 2	Family 3	Family 4	Family 5	Family 6
Area	Haikou, Hainan Province	Danzhou, Hainan Province	Wenchang, Hainan Province	Dongfang, Hainan Province	Haikou, Hainan Province	Qionghai, Hainan Province
Age (yr)	30	22	28	32	24	32
Sex	M	F	M	F	F	F
Ethnicity	Han	Han	Han	Han	Han	Han
Occupation	Office worker	Office worker	Civil servant	Office worker	Civil servant	Civil servant
Height (cm)	170	158	172	153	158	160
Visiting time	2016	2015	2014	2014	2016	2016
Reasons for medical visit	Infertility after 3 yr of marriage	Small uterus, irregular menstruation	Not pregnant after arrested fetal development	Not pregnant after two times of spontaneous abortion	Not pregnant after arrested fetal development for one time	Not pregnant after arrested fetal development for two times
Pregnancy history of self or spouse	G0P0	Unmarried	G2P0	G2P0	G1P0	G3P0
Proband karyotype	46,XY,t(3;12)(q27;q24.1)(Database number: 4222)	46,XX,t(4;16)(q31;q12)	46,XY,t(4;5)(q33;q13),9qh+	46,XX,t(11;17)(q13;p11.2)(Database number: 4059)	46,XX,t(10;13)(q24;q21.2)(Database number: 4238)	46,XX,t(1;4)(p36.1;q31.1)(Database number: 4223)
Spouse karyotype	46,XX	0	46,XX	46,XY	46,XY	46,XY
Spouse’s age	30	0	25	38	28	35