Adult-onset mitochondrial encephalopathy in association with the MT-ND3 T10158C mutation exhibits unique characteristics: A case report

Figure 1 Magnetic resonance imaging of the present patient during her second hospitalization. Axial brain magnetic resonance imaging showed marked hyperintensity on diffusion-weighted imaging (A), slight hypointensity on apparent diffusion coefficient maps (B) in the bilateral temporal cortical regions, predominantly on the left side, with hyperintensity in the corresponding region on coronal fluid-attenuated inversion recovery (D). No hypointensity of dilated intrasulcal venous structures was observed on susceptibility weighted imaging (C), and no abnormalities were observed on magnetic resonance angiography (E) or magnetic resonance venography (F). Magnetic resonance spectroscopy revealed an inverted lactate (Lac) doublet in the subcortical region of the left temporal lesion (G).