Two case reports and literature review for hepatic epithelioid angiomyolipoma: Pitfall of misdiagnosis

doi:10.12998/wjcc.v7.i8.972

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World Journal of Clinical Cases

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World J Clin Cases. Apr 26, 2019; 7(8): 972-983
Published online Apr 26, 2019. doi: 10.12998/wjcc.v7.i8.972

Table 5 Immunohistochemistry markers of hepatic epithelioid angiomyolipoma

Markers	Positive/weakly positive/negative (+/±/-)	Positive rate
HMB45	219/2/5	97.35%
S-100	19/5/63	24.71%
SMA	128/15/32	77.43%
MSA	4/10/1	60%
Actin	32/1/5	85.53%
Melan-A	91/1/22	80.70%
CD31	2/0/2	50%
CD34	38/0/34	52.78%
CD68	2/6/5	33.33%
CD117	0/0/13	0%
Vimentin	23/11/17	55.88%
Kpan	0/0/101	0%
HepPar-1	0/0/52	0%
MAC387	6/0/0	100%
EMA	0/0/30	0%
Desmin	0/20/30	20%
MART-1	24/0/1	96%
CEA	1/0/9	10%
AFP	0/1/66	0.75%
MPO	0/1/1	25%
p53	0/0/9	0%
E-cadherin, b-cadherin	0/1/4	10%
pp70S6K	1/2/1	50%
MyoD1	2/2/1	60%

HMB45: Human melanoma black 45; SMA: Smooth muscle actin; MSA: Muscle specific actin; Melan-A: Melanoma antigen; EMA: Epithelial membrane antigen; CEA: Carcino-embryonic antigen; AFP: Alpha fetoprotein; MPO: Human myeloperoxidase.

Citation: Mao JX, Teng F, Liu C, Yuan H, Sun KY, Zou Y, Dong JY, Ji JS, Dong JF, Fu H, Ding GS, Guo WY. Two case reports and literature review for hepatic epithelioid angiomyolipoma: Pitfall of misdiagnosis. World J Clin Cases 2019; 7(8): 972-983
URL: https://www.wjgnet.com/2307-8960/full/v7/i8/972.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i8.972