Bilateral adrenocortical adenomas causing adrenocorticotropic hormone-independent Cushing’s syndrome: A case report and review of the literature

Table 2 The results of peripheral 1-deamino-8-D-arginine-vasopressin stimulation test

Time	ACTH (pmol/L)	F (nmol/L)
-15 min	6.88	640.24
0 min	6.97	624.03
15 min	6.7	637.87
30 min	6.59	590.82
45 min	6.59	625.47
60 min	7.19	598.56
90 min	7.26	524.71
120 min	6.68	577.39

Normally, adrenocorticotropic hormone (ACTH) peaks between 15 min and 30 min after the infusion of DDAVP, while this patient had delayed peaking. Cushing disease is suspected if the peak level of ACTH is over 1.5 times much more than the baseline level. We can definitely diagnose it as Cushing disease if it is over 3 times. This patient’s ratio was 1.05, therefore it is not Cushing disease[30]. ACTH: Adrenocorticotropic hormone; F: Cortisol.