Association between ventricular repolarization variables and cardiac diastolic function: A cross-sectional study of a healthy Chinese population

Table 1 Clinical, electrocardiography and echocardiographic characteristics based on their E/A ratio

	All subjects (n = 414)	E/A ≥ 0.75 (n = 300)	E/A < 0.75 (n = 114)	P-value
Age (yr)	55.21 ± 14.18	55.25 ± 13.20	69.62 ± 11.05	< 0.001
Male n (%)	186 (44.9%)	124 (41.3%)	62 (55.4%)	0.017
BMI (kg/m2)	23.68 ± 3.00	23.41 ± 2.93	24.37 ± 3.08	0.004
SBP (mmHg)	125.64 ± 12.69	123.05 ± 12.68	132.43 ± 9.93	< 0.001
DBP (mmHg)	75.97 ± 8.84	74.92 ± 8.97	78.73 ± 7.87	< 0.001
TG (mmol/L)	1.38 ± 1.10	1.39 ± 1.18	1.36 ± 0.84	0.840
TC (mmol/L)	5.23 ± 1.05	5.22 ± 1.08	5.26 ± 0.98	0.722
HDL-C (mmol/L)	1.64 ± 0.41	1.65 ± 0.40	1.62 ± 0.44	0.440
LDL-C (mmol/L)	2.90 ± 0.75	2.88 ± 0.76	2.95 ± 0.70	0.448
FBG (mmol/L)	5.55 ± 0.49	5.54 ± 0.48	5.60 ± 0.53	0.248
SCr (μmol/L)	64.37 ± 14.46	62.72 ± 13.23	68.71 ± 16.58	< 0.001
PR interval (ms)	157.08 ± 23.73	156.36 ± 24.18	158.97 ± 22.50	0.302
RR interval (ms)	905.53 ± 126.29	915.40 ± 118.32	879.56 ± 142.52	0.010
QT interval (ms)	372.81 ± 30.07	371.45 ± 29.49	376.39 ± 31.40	0.136
QTc interval (ms)	393.52 ± 29.44	393.59 ± 26.74	403.86 ± 33.56	< 0.001
Tpe interval (ms)	73.94 ± 14.25	72.68 ± 12.41	77.26 ± 17.86	0.003
Tpec interval (ms)	78.27 ± 16.30	76.36 ± 13.53	83.32 ± 21.25	< 0.001
Tpe/QT	0.20 ± 0.03	0.19 ± 0.03	0.20 ± 0.04	0.004
Tpe/QTc	0.19 ± 0.03	0.19 ± 0.03	0.19 ± 0.03	0.160
E (cm/s)	74.36 ± 17.83	80.27 ± 16.20	58.82 ± 11.49	< 0.001
A (cm/s)	75.07 ± 19.21	68.75 ± 16.70	91.69 ± 15.07	< 0.001
E/A	1.07 ± 0.41	1.23 ± 0.36	0.64 ± 0.08	< 0.001
MV-DT (ms)	162.78 ± 35.15	159.43 ± 31.14	171.60 ± 42.92	0.002
LAV (mL)	33.16 ± 9.73	32.30 ± 9.70	35.42 ± 9.48	0.003
LAVI (mL/m2)	19.83 ± 5.31	19.38 ± 5.29	21.01 ± 5.22	0.005
LVEF (%)	62.54 ± 4.71	62.86 ± 4.47	61.68 ± 5.21	0.023

BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; TG: Triglyceride; TC: Total cholesterol; HDL-C-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; FBG: Fasting blood glucose; SCr: Serum creatinine; E: Early diastolic inflow velocity; A: Late diastolic inflow velocity; DT: E-wave deceleration time; LAV: Left atrial volume; LAVI: Left atrial maximum volume index; LVEF: Left ventricular ejection fraction.