Review
Copyright ©The Author(s) 2019.
World J Clin Cases. Dec 26, 2019; 7(24): 4172-4185
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4172
Figure 2
Figure 2 A model of the possible mechanisms by which polyunsaturated fatty acids can alter DNA methylation in colorectal cancer. DNMTs: DNA methyltransferases; DHA: Docosahexaenoic acid; PE-DHA: Phosphatidylethanolamine-DHA; PC-DHA: Phosphatidylcholine-DHA; PUFA: Poly unsaturated fatty acid; COX-2: Cyclooxygenase-2; PGE2: Prostaglandin E2; PPARs: Peroxisome proliferator-activated receptors; RXR: Retinoid X receptor; UHRF1: Ubiquitin-like protein containing PHD and RING finger domains 1; miRNAs: MicroRNAs; α-KG: α-ketoglutarate; TET: Ten-eleven translocation.