Case Report
Copyright ©The Author(s) 2019.
World J Clin Cases. Dec 26, 2019; 7(24): 4377-4383
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4377
Table 1 The timeline of treatment
TimeSymptomsDiagnosesTreatments
2008Canker soresUndifferentiated connective tissue diseaseLow doses of prednisone: 5 mg
White blood cell count: 1.8 × 109/L
ANA: 1:320(+)
Blood complements: Normal
Serum creatinine: 66 µmol/L
2016Facial erythemaUndifferentiated connective tissue diseaseHydroxychloroquine; Prednisone
Decreased blood complements
April 2018Weight lossUndifferentiated connective tissue disease; Hydroxychloroquine -induced renal phospholipidosisWithdrawal of hydroxychloroquine; Prednisone
Weakness
White blood count: 2.7-4.7 × 109/L
Urine erythrocytes: 28/µL
Serum creatinine: 58 µmol/L
24-h urinary protein, quantitative: 1120 mg
ANA: 1:80(+)
Complement C3: 0.58 g/L
Complement C4: 0.09 g/L
Renal biopsy: Renal phospholipidosis
Mutation of GLA gene: Negative