Case Report
Copyright ©The Author(s) 2019.
World J Clin Cases. Dec 26, 2019; 7(24): 4355-4365
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4355
Table 3 Clinical characteristics of multisystem smooth muscle dysfunction syndrome patients worldwide
CharacteristicAmans et al[12], 2014Yetman et al[13], 2015Richer et al[14], 2012De et al[6], 2016Moreno et al[7], 2016
n13121
GenderFFFFMFMF
Age(yr)3150.93120.20.8
Vision systemCongenital mydriasis++++++++
Retinal vascular tortuosity+++
Cardiovascular systemPDA++++++++
ASD-+++--++
PAH-+++++--
TAA-+-+----
AAD-++++-+-
PAD-++++-+-
Nervous systemDevelopment delay+
Spastic seizures/epilepsy+-+
Cerebral infarction/hemiplegia--------
WM signal changes-++++-+-
Moyamoya-like changes++--++++
Digestive systemIntestinal malrotation++-+
Intestinal hypoperistalsis--++
Gallstones
Respiratory systemDyspnea--+-++
RRTI------
Asthma------
Urinary systemHypotonic bladder++-++-++
Hydronephrosis-+++
Hypospadias++++
ACTA2 mutationHHHHHCCC
PrognosisDD