Distant metastasis in choroidal melanoma with spontaneous corneal perforation and intratumoral calcification: A case report

Figure 5 Histological findings of the fine needle aspiration specimens. A: Specimen from the fine needle aspiration of liver tumor showed sheets of epithelioid and spindle neoplastic cells arranged in a solid pattern with occasional prominent nucleoli and eosinophilic cytoplasm that exhibited stromal reaction and abundant melanin pigment (×400); B: Immunohistochemistry (IHC) revealed diffusely positive melanin-A immunostaining in the cytoplasm of metastatic neoplastic cells (Red chromogen, ×400); C: IHC revealed diffusely positive SOX-10 immunostaining in the nuclei of metastatic neoplastic cells (Red chromogen, ×400); D: The epithelioid metastatic tumor cells showed strong nuclear labeling for BAP1 expression (Red chromogen, ×400).