Interaction of arylsulfatases A and B with maspin: A possible explanation for dysregulation of tumor cell metabolism and invasive potential of colorectal cancer

Table 4 Correlation between maspin expression and pathological aspects of colorectal cancer

Characteristics	Number	Maspin expression		P value
		Negative	Positive
Age, yr
≤ 60	19	9	10	0.661
> 60	26	14	12
Gender
Male	26	13	13	0.861
Female	19	10	9
Macroscopic aspect
Polypoid	12	10	2	0.011
Ulcero-infiltrative	33	13	20
Microscopic aspect
G1	14	11	3	0.032
G2	24	10	14
G3+4	7	2	5
Localization
Proximal	8	1	7	< 0.00012
Distal	21	19	2
Upper rectum	16	3	13
Lymph node ratio
< 0.1	34	19	15	0.261
≥ 0.1	11	4	7
Lymph node metastasis
Absent	29	19	10	0.011
Present	16	4	12
pT stage
≤ T2	15	13	2	0.0011
≥ T3	30	10	20
Budding grade
G1	15	14	1	<0.0011
G2	9	5	4
G3	21	4	17

¹Fisher’s exact test.

²χ² test. Significant differences are shown in bold. G1: Well differentiated; G2: Moderately differentiated; G3: Poorly differentiated, 4 mucinous.