Value of elastography point quantification in improving the diagnostic accuracy of early diabetic kidney disease

Table 1 Differences of clinical data, laboratory indicators and ultrasound indicators in diabetes group, early diabetic kidney disease group, and medium diabetic kidney disease group

	Diabetes group (n = 40)	Early DKD group (n = 36)	Medium DKD group (n = 33)	F/X2 value	P value
Gender (Male/Female)	21/19	20/16	17/16	0.126	0.939
Age (yr)	56.61 ± 10.11	55.21 ± 10.56	57.53 ± 11.46	0.973	0.412
Diabetes duration (yr)	3.55 ± 1.65	5.44 ± 1.70a	6.73 ± 5.69a	4.931	0.003
Systolic blood pressure (mmHg)	128.2 ± 19.60	130.0 ± 18.40	133.5 ± 22.10	1.735	0.162
Diastolic blood pressure (mmHg)	76.6 ± 16.50	80.1 ± 15.40	82.5 ± 16.20	1.836	0.146
Blood glucose (mmol/L)	4.9 ± 0.6	5.5 ± 1.1	5.9 ± 1.3	1.022	0.388
HBA1C (%)	6.80 ± 1.25	7.22 ± 1.66	7.54 ± 1.38	2.391	0.073
UAER (mg/24 h)	13.94 ± 1.85	15.35 ± 8.71a	61.74 ± 23.72ab	5.822	< 0.001
BUN (mmol/L)	4.91 ± 2.04	5.73 ± 1.23	6.59 ± 2.45a	3.702	0.014
Scr (μmol/L)	55.83 ± 14.12	61.75 ± 11.20	69.23 ± 13.56a	4.523	0.005
Ccr (ml/min)	105.12 ± 15.1	98.23 ± 17.1	83.57 ± 23.7a	3.821	0.012
CysC (mg/L)	0.73 ± 0.49	1.06 ± 0.67	1.79 ± 0.88a	3.044	0.032
UA (μmol/L)	249.31 ± 60.45	256.22 ± 58.24	266.84 ± 54.26	2.251	0.087
TG (mmol/L)	1.85 ± 1.36	1.92 ± 1.55	2.03 ± 1.42	2.362	0.075
HDL (mmol/L)	1.25 ± 0.35	1.09 ± 0.23	1.13 ± 0.35	1.703	0.172
LDL (mmol/L)	2.66 ± 0.55	2.85 ± 0.57	2.82 ± 0.55	2.022	0.115
YM (kPa)
Renal cortex	5.51 ± 1.53	7.93 ± 2.66a	16.68 ± 4.48ab	0.383	0.021
Renal medullary	4.29 ± 1.62	6.67 ± 3.22	8.32 ± 3.56	2.571	0.058
Renal sinus	2.89 ± 1.32	3.46 ± 1.24	3.81 ± 1.05	2.493	0.064
Renal artery RI	0.64 ± 0.06	0.69 ± 0.08	0.76 ± 0.09a	3.182	0.027
Renal volume (mL)	105 ± 16.91	116 ± 17.10	112 ± 16.35	2.044	0.113
Renal parenchymal thickness (mm)	13.89 ± 2.66	14.57 ± 1.87	10.99 ± 1.83ab	3.181	0.015

^aP < 0.05 vs the diabetes group;

^bP < 0.05 vs the early diabetic kidney disease group. DKD: Diabetic kidney disease; HBA1C: Hemoglobin A1C; UAER: Urinary albumin excretion rate; BUN: Blood urea nitrogen; Scr: Serum creatinine; Ccr: Creatinine clearance; CysC: Cystatin C; UA: Urinary albumin; TG: Triglyceride; HDL: High density lipoprotein cholesterol; LDL: Low density lipoprotein cholesterol; YM: Young's Modulus; RI: Resistance index.