Copyright
©The Author(s) 2019.
World J Clin Cases. Nov 6, 2019; 7(21): 3622-3631
Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3622
Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3622
Patient 0 (case) | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
Age in yr | 1 | 4 | < 1 (8 m) | 1 | 5 | 2 |
Sex | Male | Male | Male | Male | Male | Male |
Time for UCBT | 2017/10/15 | 2017/6/3 | 2018/6/8 | 2018/3/24 | 2017/7/7 | 2017/12/15 |
CD34 dose | 4.7 × 105/kg | 2 × 105/kg | 4.92 × 105/kg | 2.4 × 1055/kg | 4.55 × 105/kg | 3.0 × 105/kg |
TNC | 9.17 × 107/kg | 6.73 × 107/kg | 15.3 × 107/kg | 11.1 × 107/kg | 6.26 × 107/kg | 9.23 × 107/kg |
Conditional regimen | Bu + Flu + CTX + ATG | BU + Flu + CTX + ATG | BU + Flu + CTX + ATG | BU + Flu + CTX + ATG | BU + Flu + CTX + ATG | BU + Flu + CTX + ATG |
HLA (/6) | 4/6 | 6/6 | 6/6 | 5/6 | 5/6 | 4/6 |
HLA (/10) | 6/10 | 9/10 | 10/10 | 9/10 | 8/10 | 6/10 |
Blood type (patient/donor) | B/B | A/O | B/B | O/O | O/O | A/AB |
Neutrophil grafted time | D34 | D16 | D13 | D15 | D17 | D14 |
Lymphocytes>0.5 × 109/L | D23 | D28 | D42 | D17 | D30 | D65 |
PLT grafted time | D66 | D28 | D29 | D30 | D33 | D27 |
Main complication | No | Hemorrhagic cystitis | Infection by Pneumocystis carinii | No | Intestinal infection | Leak syndrome, hemorrhagic cystitis |
- Citation: Li BH, Hu SY. Child with Wiskott–Aldrich syndrome underwent atypical immune reconstruction after umbilical cord blood transplantation: A case report. World J Clin Cases 2019; 7(21): 3622-3631
- URL: https://www.wjgnet.com/2307-8960/full/v7/i21/3622.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v7.i21.3622