Nomograms for pre- and postoperative prediction of long-term survival among proximal gastric cancer patients: A large-scale, single-center retrospective study

Table 3 Postoperative analysis of overall survival

	Univariate analysis		Multivariate analysis
Variable	HR (95%CI)	P value	HR (95%CI)	P value
Postoperative T stage		< 0.001		0.005
T1	Ref		Ref
T2	2.743 (1.054-7.139)		2.210 (0.843-5.794)
T3	6.359 (2.759-14.657)		2.730 (1.130-6.594)
T4a	9.829 (4.345-22.235)		3.847 (1.595-9.278)
Postoperative N stage		< 0.001		< 0.001
N0	Ref		Ref
N1	1.371 (0.820-2.290)		0.962 (0.564-1.639)
N2	1.984 (1.250-3.151)		1.251 (0.767-2.041)
N3	5.967 (4.109-8.663)		2.659 (1.708-4.139)
Postoperative tumor size(cm)		< 0.001		0.022
< 5	Ref		Ref
≥ 5	2.938 (2.172-2.973)		1.503 (1.060-2.132)
Lymphatic vascular infiltration (LVI)		< 0.001		< 0.001
No	Ref		Ref
Yes	3.185 (2.447-4.146)		2.690 (2.036-3.554)
Postoperative blood transfusion		< 0.001		0.025
No	Ref		Ref
Yes	1.971 (1.402-2.771)		1.505 (1.052-2.153)
General complications		0.001		0.028
No	Ref		Ref
Yes	1.784 (1.278-2.490)		1.477 (1.042-2.093)
Digestive tract fistula		0.125
No	Ref
Yes	2.001 (0.825-4.855)
Postoperative obstruction		0.033
No	Ref
Yes	2.629 (1.083-6.386)
Incisional infection		0.984
No	Ref
Yes	0.986 (0.245-3.966)
Abdominal infection		0.964
No	Ref
Yes	1.021 (0.421-2.476)
Pulmonary infection		0.001
No	Ref
Yes	2.104 (1.378-3.211)
Peritoneal lymphatic fistula		0.565
No	Ref
Yes	1.297 (0.535-3.147)
intra-Abdominal hemorrhage		0.093
No	Ref
Yes	2.136 (0.880-5.181)
Tumor involvement of the esophagus		0.328
No	Ref
Yes	1.141 (0.876-1.487)
Neoadjuvant chemotherapy		0.012
No	Ref
Yes	2.480 (1.225-5.022)
Adjuvant chemotherapy
No	Ref
Yes	1.166 (0.902-1.507)	0.242
Lymph node ratio	1.697 (0.998-2.867)	0.053