Current controversies in treating remnant gastric cancer: Are minimally invasive approaches feasible?

Table 3 Clinical outcomes of laparoscopic surgery for remnant gastric cancer

Ref.	Type of procedure	No. of patients	Conver-sion to open surgery	Operative time (min)	Blood loss	Retrieved lymph-node	Postopera-tive hospital stay	Complica-tions	Follow-up (mo)	5-yr OS
Nagai et al[60], 2014	LG	12	0	362.3 ± 68.4	68.5 ± 62 g	23.7 ± 10.7	11.3 ± 2.8	0	39.1 ± 20.5	77.80%
	OG	10	NA	270.5 ± 94.9	746.3 ± 577.1 g	15.7 ± 7.6	24.9 ± 10	20%	62.7 ± 39.8	72.90%
Son et al[61], 2015	LG	17	47.10%	234.4 ± 65.2	227.6 ± 245.0 mL	18.8 ± 12.3	9.3 ± 3.2	35.20%	23.6	66.70%
	OG	17	NA	170.0 ± 39.5	184.1 ± 123.1 mL	22.3 ± 14.4	9.3 ± 3.1	29.40%	37.3	60.30%
Kwon et al[62], 2014	LG	18a	5.60%	266.2 ± 77.2	182.2 ± 188.7 mL	8	6	33.30%	25.2	94.90%
	OG	58	NA	203.3 ± 52.2	193.1 ± 227.6 mL	7	9	44.80%		100%
Kim et al[63], 2014	LG	17	0	197.2 ± 60.6	NA	NA	11.1 ± 8.7	30%	NA	NA
	OG	50	NA	149.3 ± 46.9	NA	NA	13.8 ± 9.4	23.50%	NA	NA
Tsunoda et al[64], 2016	LG	10	0	324.5 ± 42.8	55 g	22.4 ± 15.8	12.5 ± 2.9	10	NA	NA
	OG	6	NA	289	893 g	7	24	33.30%	NA	NA
Luo et al [65], 2015	LG	9	0	221.1 ± 19.5	105.5 ± 35.04 mL	16.2 ± 3	NA	11.10%	NA	NA
	OG	9	NA	212.9 ± 14.3	147.7 ± 41.92 mL	16.7 ± 3.3	NA	22.20%	NA	NA
Booka et al[66], 2019	LG	8	25%	307.5 ± 56.0	135.5 ± 181.2 mL	8.8 ± 4.6	10.6 ± 3.7	37.50%	NA	NA
	OG	23	NA	295.8 ± 81.7	568.3 ± 446.4 mL	6.0 ± 6.9	21.3 ± 37.3	26.10%	NA	NA
Nakaji et al[67], 2019	LG	4	0	455	158 mL	15	15	50%	NA	94%
	OG	18	NA	293	625 mL	11	16	27.80%	NA
Otsuka et al[68], 2019	LG	7	0	364 ± 95	70 ± 71 g	22 ± 13	13 ± 5	28.60%	NA	NA
	OG	20	NA	309 ± 104	1066 ± 1428 g	12 ± 9	27 ± 21	50%	NA	NA
Kaihara et al[69], 2019	LG	6	17%	310.5	50 mL	7	9	50%	21	88%
	OG	15	NA	263	465 mL	3	9	33%		60.60%

^aTen laparoscopic gastrectomy, eight robotic gastrectomy. LG: Laparoscopic Gastrectomy; OG; Open Gastrectomy; NA: Not applicable; OS: Overall survival.