Clinical use of low-dose aspirin for elders and sensitive subjects

Table 2 Non-use of aspirin and incidence of upper gastrointestinal bleeding

Study type (dose)	Subject number (M/F)	Age in yr	Study duration	Inclusion/Ex-clusion criteria	Conclusion	Title
Comparison of using or non-using LDA in bleeding in elders	76 (40/36)	> 65	10/2015-11/2017	Gastric ulcer	45% LDA users with upper gastrointestinal bleeding vs only 8% without the use	Clinical study of gastrointestinal bleeding in elderly patients with the use of LDA[48]
Interventional study of LDA in the upper GI bleeding	112 (71/41)	Mean 62.3	03/2010-05/2012	LDA use (100 mg) and upper GI bleeding	Stop the use of LDA, but use other drug lead stop of bleeding 69/112 in 3 d	Clinical analysis of upper gastrointestinal bleeding from aspirin use[49]

LDA: low-dose aspirin; M: Male; F: Female; GI: Gastrointestinal.