Association of stiff-person syndrome with autoimmune endocrine diseases

doi:10.12998/wjcc.v7.i19.2942

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Oct 6, 2019 (publication date) through Feb 7, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 6, 2019; 7(19): 2942-2952
Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2942

Table 5 Coexisting diseases and related autoantibodies in stiff-person syndrome patients

Autoimmune disease	Associated antibody	Neoplasm	Associated antibody
Type 1 DM	Anti-GAD Anti-IA2	Breast cancer	Gephyrin
LADA	Anti-GAD Anti-IA2	Lung cancer	Amphiphysin
Hashimoto’s thyroiditis	Anti-TPO, ATA, anti-TSHR	Thyroid cancer	ATA
Graves’ disease	Anti-TPO, ATA, anti-TSHR	Colon cancer
Pernicious anemia	Anti-parietal cells	Renal cell carcinoma
Celiac disease	Anti-transglutaminase antibodies (anti-tTG), anti-endomysial antibodies	Thymoma	Anti-AchR
Myasthenia graves	Anti-AchR	Neuroendocrine tumor
Sjögren syndrome	ANA, anti-Ro	Hodgkin lymphoma
Systemic lupus erythematosus	ANA, ds-DNA	Multiple myeloma
Vitiligo
Autoimmune polyglandular Syndrome type 1 or type 2 or type 3

DM: Diabetes mellitus; LADA: Latent autoimmune diabetes in adults; GAD: Glutamic acid decarboxylase; IA-2: Islet antigen 2; TPO: Thyroid peroxidase; ATA: Anti-thyroglobulin antibody; AchR: Acetylcholine receptor; ANA: Anti-nuclear antibody; TSHR: Thyroid-stimulation hormone receptor.

Citation: Lee YY, Chen IW, Chen ST, Wang CC. Association of stiff-person syndrome with autoimmune endocrine diseases. World J Clin Cases 2019; 7(19): 2942-2952
URL: https://www.wjgnet.com/2307-8960/full/v7/i19/2942.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i19.2942