Characterization of microbiota in systemic-onset juvenile idiopathic arthritis with different disease severities

Figure 1 Box plots of observed species, Chao1 index, and Shannon and Simpson indices of microbiota for healthy subjects and systemic-onset juvenile idiopathic arthritis patients with different disease activities. Medians and interquartile ranges are shown. The significance of differences was calculated using the Kruskal-Wallis test with Bonferroni correction. ^aP < 0.001, A-SoJIA vs HS in observed species; ^bP < 0.01, Ina-SoJIA vs HS in observed species; ^cP < 0.001, A-SoJIA vs HS in Chao1; ^dP < 0.01, Ina-SoJIA vs HS in Chao1. SoJIA: Systemic-onset juvenile idiopathic arthritis; A-SoJIA: Active-SoJIA; Ina-SoJIA: Inactive-SoJIA; HS: Healthy subjects.