Mycobacterium chimaera infections following cardiac surgery in Treviso Hospital, Italy, from 2016 to 2019: Cases report

Table 2 Clinical features of Mycobacterium chimaera infections and selected laboratory abnormalities of Mycobacterium chimaera infected patients at presentation in United Kingdom and Treviso patients (modified, from Scriven et al[16], 2018)

Variable	UK patients (n = 30)	Italian patients (n = 9)
Clinical finding, n (%)
Fever	24 (80)	7 (78)
Malaise (astenia)	24 (80)	7 (78)
Weight loss	18 (60)	6 (66)
Cough	11 (37)	3 (33)
Dyspnoea	10 (33)	2 (22)
Arthralgia	6 (20)	0
Chest pain	6 (20)	0
Abdominal pain	3 (10)	0
Back pain	2 (7)	5 (55)
New cardiac murmur	9 (30)	6 (66)
Oedema	6 (20)	1 (11)
Crepitations	6 (20)	0
Splenomegaly	8 (27)	6 (66)
Hepatomegaly	6 (20)	3 (33)
Lymphadenopathy	1 (3)	1 (11)
Sternal wound	4 (13)	0
Skin lesion	2 (7)	0
Choroiditis	2 (7)	5 (55)
Neurological symptoms	NA	5 (55)
Laboratory findings, median (IQR)
Haemoglobin (g/L)	110 (96-127)	105 (95-114)
WBC (× 109/L)	3.9 (2.2-5.4)	3.9 (2.8-6.7)
Neutrophils (× 109/L)	2.4 (1.3-3.3)	2.6 (1.4-3.8)
Lymphocytes (× 109/L)	0.9 (0.6-1.3)	0.76 (0.56–1.05)
Platelets (× 109/L)	175 (86-223)	166 (76-257)
Albumin (g/L)	30 (26-37)	34 (27-39)
ALT (IU/L)	43 (33-85)	41 (15-70)
ALP (IU/L)	256 (132-357)	242 (157-254)
Sodium (µmol/L)	134 (131-136)	131 (128-136)
eGFR (mL/min)	66 (53-80)	52 (35-81)
CRP (mg/L)	33 (17-46)	19 (14-31)
ESR (mm/h)	NA	65 (36-111)
LDH (IU/L)	NA	463 (244-680)
gammaGT (IU/L)	NA	104 (44-156)

ALP: Alkaline phosphatase; ALT: Alanine transaminase; CRP: C-reactive protein; eGFR: Estimated glomerular filtration rate; ESR: Erythrocyte sedimentation rate; gammaGT: Gammaglutamiltranspeptidase; IQR: Interquartile range; LDH: Lactate dehydrogenase; NA: Not available; WBC: White blood count.