Mycobacterium chimaera infections following cardiac surgery in Treviso Hospital, Italy, from 2016 to 2019: Cases report

Table 1 Clinical features and outcome

Case	sex/age	Cardiac surgery	Date surgery	Symptoms beginning	Date hospitali-zation	Micro-biological diagnosis (date) and disease history	Clinical syndromes	Medical therapy (mo)	Repeat surgery and disease history	Outcome
1	M 37	CARR	12/2012 TH	After 35 mo	05/2016	09/2016, after 10 mo	PVE, AAP, DI	Anti-MAC (1)	After 8 mo	Deceased
2	M 60	AVR + MVA	01/2013 oH	After 40 mo	05/2016	10/2016, after 11 mo	PVE, AAP, DI	No	No (see text)	Deceased
3	M 42	AVR + ARR	05/2015 TH	After 6 mo	10/2016	11/2016, after 12 mo	PVE, AAP, DI	No	No	Deceased
4	M 75	AVR	02/2011 TH	After 64 mo	07/2016	01/2017, after 7 mo	PVE, DI, SD	Anti-MAC (13)	After 15 mo	Deceased
5	M 80	MVR + AW	03/2016 TH	After 12 mo	08/2018	09/2018, after 18 mo	PVE, SD	Targeted (14)	No	On therapy
6	M 56	AVR	06/2016 TH	After 27 mo	11/2018	10/2018, after 1 mo	PVE, DI, SD	Targeted (12)	After 8 mo	On therapy
		ARR	05/2015 TH
7	M 75	AVR	01/2014 oH	After 21 mo	02/2019	04/2019, after 8 months	PVE	Targeted (4)	No	On therapy
		AVR	11/2016 oH
8	M 76	AVR + CABG	02/2011 TH	After 97 mo	05/2019	05/2019, after 2 mo	PVE, DI, SD	Targeted (3)	No	On therapy
9	M 82	AVR + CABG	08/2016 oH	After 12 mo	06/2019	06/2019, after 22 mo	PVE	Targeted (2)	No	On therapy

AAP: Ascending aortic pseudoaneurysm; ARR: Aortic root replacement; AVR: Aortic valve replacement; AW: Ascending aortic wrapping; CABG: Coronary artery bypass graft; cARR: Composite aortic root replacement; DI: Disseminated infection; MVA: Mitral valve annuloplasty; oH: Other hospital; PVE: Prosthetic valve endocarditis; SD: Spondylodiscitis; TH: Treviso Hospital; MAC: Mycobacterium avium complex.