Prognostic significance of 14v-lymph node dissection to D2 dissection for lower-third gastric cancer

Table 2 Univariate and multivariate analyses of prognostic factors for the entire study population

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95%CI)	P-value	Hazard ratio (95%CI)	P-value
Status of 14v dissection		0.980		0.900
14vD (-)	1 (ref)		1 (ref)
14vD (+)	1.01 (0.64-1.58)		0.97 (0.59-1.60)
Age group		0.569		0.234
< 65 yr	1 (ref)		1 (ref)
≥ 65 yr	1.15 (0.71-1.86)		1.40 (0.80-2.45)
Gender		0.781
Male	1 (ref)		1 (ref)	0.721
Female	0.94 (0.60-1.46)		0.91 (0.56-1.50)
Tumor size		0.455		0.448
< 4 cm	1 (ref)		1 (ref)
≥ 4 cm	1.19 (0.76-1.86)		0.82 (0.50-1.56)
Histologic grade		0.275		0.162
Differentiated	1 (ref)		1 (ref)
Undifferentiated	1.34 (0.80-2.24)		1.51 (0.85-2.71)
pT stage		0.004		0.033
T1	1 (ref)		1 (ref)
T2	4.88 (1.13-20.99)		4.97 (1.11-22.28)
T3	8.32 (1.96-35.29)		6.58 (1.45-29.92)
T4	9.17 (2.2-38.21)		7.87 (1.84-33.74)
pN stage		0.002		0.018
N0	1 (ref)		1 (ref)
N1	2.29 (1.07-4.90)		2.08 (0.92-4.67)
N2	2.18 (1.20-3.97)		2.01 (1.06-3.81)
N3a	3.11 (1.71-5.63)		2.82 (1.49-5.36)
N3b	4.30 (1.46-12.65)		3.90 (1.22-12.45)
Postoperative chemotherapy		0.799		0.368
No	1 (ref)		1 (ref)
Yes	1.06 (0.67-1.70)		0.78 (0.46-1.33)