Reduced microRNA-451 expression in eutopic endometrium contributes to the pathogenesis of endometriosis

Figure 3 Transfection with miR-451 siRNA decreases apoptosis and promotes cell proliferation in control eutopic cells. A: MiR-451 expression was significantly inhibited after transfection with miR-451 siRNA. Data are expressed as 2^−ΔΔCt (mean ± SEM, n = 4). ^bP < 0.01 vs control and scrambled; B: Cell Counting Kit-8 assays revealed that the proliferation rate of cells transfected with miR-451 siRNA was higher than those of cells in the control and scrambled groups (^aP < 0.05); C and D: Flow cytometric analysis of apoptosis in cells transfected with scrambled siRNA and miR-451, respectively.