Application of Newcastle disease virus in the treatment of colorectal cancer

doi:10.12998/wjcc.v7.i16.2143

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Aug 26, 2019 (publication date) through Jul 26, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Aug 26, 2019; 7(16): 2143-2154
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2143

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Figure 3 Bispecific antibodies consisting of single-chain variable regions can be simultaneously targeted to viruses and immune cells. When NDV infects tumor cells, bispecific antibodies can target F or HN on the surface of tumor cells and can simultaneously target CD3, CD25 or CD28 on the surface of immune T cells. F: Fusion protein; HN: Hemagglutinin-neuraminidase; NDV: Newcastle disease virus.

Citation: Song H, Zhong LP, He J, Huang Y, Zhao YX. Application of Newcastle disease virus in the treatment of colorectal cancer. World J Clin Cases 2019; 7(16): 2143-2154
URL: https://www.wjgnet.com/2307-8960/full/v7/i16/2143.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i16.2143