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Copyright ©The Author(s) 2019.
World J Clin Cases. Aug 26, 2019; 7(16): 2143-2154
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2143
Figure 3
Figure 3 Bispecific antibodies consisting of single-chain variable regions can be simultaneously targeted to viruses and immune cells. When NDV infects tumor cells, bispecific antibodies can target F or HN on the surface of tumor cells and can simultaneously target CD3, CD25 or CD28 on the surface of immune T cells. F: Fusion protein; HN: Hemagglutinin-neuraminidase; NDV: Newcastle disease virus.