Copyright
©The Author(s) 2019.
World J Clin Cases. Aug 26, 2019; 7(16): 2143-2154
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2143
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2143
Figure 3 Bispecific antibodies consisting of single-chain variable regions can be simultaneously targeted to viruses and immune cells.
When NDV infects tumor cells, bispecific antibodies can target F or HN on the surface of tumor cells and can simultaneously target CD3, CD25 or CD28 on the surface of immune T cells. F: Fusion protein; HN: Hemagglutinin-neuraminidase; NDV: Newcastle disease virus.
- Citation: Song H, Zhong LP, He J, Huang Y, Zhao YX. Application of Newcastle disease virus in the treatment of colorectal cancer. World J Clin Cases 2019; 7(16): 2143-2154
- URL: https://www.wjgnet.com/2307-8960/full/v7/i16/2143.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v7.i16.2143