Surveillance and diagnosis of hepatocellular carcinoma: A systematic review

Table 1 Studies about the advantages and results of surveillance in HCC

Ref.	Location	Inclusion period	n	Screening (%)	Results surveillance group
	UNI/MULTI
Edenvik et al[21]	Sweden UNI	2005-2012	616	22%	Better survival
van Meer et al[22]	Netherlands MULTI	2005-2012	1074	27%	Smaller tumor size, earlier tumor stage, more often curative treatment and improving 1, 3, 5 years survival rates
Singal et al[23]	United States MULTI	2012-2013	374	42%	Early tumor detection and improved survival
Mittal et al[24]	United States MULTI	2005-2010	887	46.5%	Reduction in mortality
Atiq et al[25]	United States UNI	2010-2013	680	11.5%	Early HCC

UNI: Uni-center; MULTI: Multicenter; HCC: Hepatocellular carcinoma.