Copyright
©The Author(s) 2019.
World J Clin Cases. Aug 26, 2019; 7(16): 2176-2188
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2176
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2176
Table 1 Baseline characteristics of the cohorts
Training cohort (n = 309) | Validation cohort (n = 331) | P-value | |||
No. of patients | Percent | No. of patients | Percent | ||
Gender | 0.197 | ||||
Male | 266 | 86.1 | 296 | 89.4 | |
Female | 43 | 13.9 | 35 | 10.6 | |
Age, yr | 0.095 | ||||
Median | 56 | 55 | |||
IQR | 48-63 | 48-61 | |||
BMI, kg/m2 | 0.111 | ||||
Median | 22.7 | 23.0 | |||
IQR | 20.6-24.8 | 21.1-27.2 | |||
ASA score | 0.395 | ||||
1 | 61 | 19.7 | 80 | 24.2 | |
2 | 210 | 68.0 | 214 | 64.6 | |
3 | 38 | 12.3 | 37 | 11.2 | |
Smoking | 0.241 | ||||
Yes | 136 | 44.0 | 161 | 48.6 | |
No | 173 | 56.0 | 170 | 51.4 | |
Alcohol consumption | 0.140 | ||||
Yes | 159 | 51.5 | 151 | 45.6 | |
No | 150 | 48.5 | 180 | 54.4 | |
Diabetes | 0.616 | ||||
Yes | 29 | 9.4 | 35 | 10.6 | |
No | 280 | 90.6 | 396 | 89.4 | |
Etiology | 0.204 | ||||
Hepatitis B | 227 | 73.5 | 243 | 73.4 | |
Hepatitis C | 12 | 3.9 | 7 | 2.1 | |
Child-Pugh grade | 0.562 | ||||
A | 295 | 95.5 | 319 | 96.4 | |
B and C | 14 | 4.5 | 12 | 3.6 | |
TNM stage | 0.201 | ||||
I | 148 | 47.9 | 139 | 42.0 | |
II | 114 | 36.9 | 125 | 37.8 | |
IIIa | 17 | 5.5 | 34 | 10.2 | |
IIIb | 28 | 9.1 | 30 | 9.1 | |
IVa | 2 | 0.6 | 3 | 0.9 | |
IVb | 0 | 0 | 0 | 0 | |
Cirrhosis | 0.130 | ||||
Yes | 218 | 70.6 | 215 | 65.0 | |
No | 91 | 29.4 | 116 | 35.0 | |
AFP, ng/mL | 0.876 | ||||
Median | 65.8 | 74.8 | |||
IQR | 8.7-479.8 | 8.4-754.2 | |||
ALT, U/L | 0.126 | ||||
Elevated | 109 | 35.3 | 98 | 29.6 | |
Normal | 200 | 64.7 | 232 | 70.4 | |
AST, U/L | 0.219 | ||||
Elevated | 139 | 44.9 | 133 | 40.2 | |
Normal | 170 | 55.1 | 198 | 59.8 | |
Albumin, g/L | 0.316 | ||||
Median | 40.6 | 40.1 | |||
IQR | 36.7-43.9 | 37.5-42.7 | |||
TB, μmol/L | 0.410 | ||||
Median | 14.2 | 14.7 | |||
IQR | 11.3-18.6 | 11.6-18.4 | |||
INR | 0.792 | ||||
Median | 1.04 | 1.04 | |||
IQR | 0.98-1.10 | 0.98-1.10 | |||
Hb, g/L | 0.504 | ||||
Median | 145 | 147 | |||
IQR | 132-156 | 135-155 | |||
PLT, 109/L | 0.141 | ||||
Median | 142 | 138 | |||
IQR | 106-192 | 102-178 | |||
ICG15% | 0.775 | ||||
Median | 5.4 | 5.8 | |||
IQR | 3.0-8.6 | 2.8-8.5 | |||
History of RFA | 0.228 | ||||
Yes | 13 | 4.2 | 21 | 6.3 | |
No | 296 | 95.8 | 310 | 93.7 | |
History of TACE | 0.584 | ||||
Yes | 8 | 2.6 | 11 | 3.3 | |
No | 301 | 97.4 | 320 | 96.7 | |
Repeat hepatectomy | 0.868 | ||||
Yes | 48 | 15.6 | 53 | 16.0 | |
No | 261 | 84.4 | 278 | 84.0 | |
Type of hepatectomy | 0.109 | ||||
Major | 81 | 35.2 | 69 | 20.8 | |
Minor | 228 | 64.8 | 262 | 79.2 | |
Duration of surgery, min | 0.351 | ||||
Median | 237 | 223 | |||
IQR | 184-302 | 183-292 | |||
Blood Loss, mL | 0.215 | ||||
Median | 160 | 220 | |||
IQR | 80-400 | 110-330 | |||
Intraoperative blood transfusion | 0.305 | ||||
Yes | 63 | 20.4 | 57 | 17.2 | |
No | 246 | 79.6 | 274 | 82.8 | |
Surgical site infection | 0.840 | ||||
Yes | 33 | 10.7 | 37 | 11.2 | |
Grade II | 21 | 6.8 | 23 | 6.9 | |
Grade IIIa | 7 | 2.3 | 9 | 2.7 | |
Grade IIIb | 2 | 0.6 | 1 | 0.3 | |
Grade IVa | 2 | 0.6 | 2 | 0.6 | |
Grade IVb | 0 | 0 | 1 | 0.3 | |
Grade V | 1 | 0.3 | 1 | 0.3 | |
No | 276 | 89.3 | 294 | 88.8 | |
Hospital stay, d | 0.323 | ||||
Median | 8 | 8 | |||
IQR | 6-11 | 6-12 |
- Citation: Tang TY, Zong Y, Shen YN, Guo CX, Zhang XZ, Zou XW, Yao WY, Liang TB, Bai XL. Predicting surgical site infections using a novel nomogram in patients with hepatocelluar carcinoma undergoing hepatectomy. World J Clin Cases 2019; 7(16): 2176-2188
- URL: https://www.wjgnet.com/2307-8960/full/v7/i16/2176.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v7.i16.2176