Clinical significance and role of up-regulation of SERPINA3 expression in endometrial cancer

Table 1 Relationship between SERPINA3 expression and pathologic features of endometrial cancer

Variable		N	SERPINA3 protein		X2	P-value
			-	+
Pathological grade	I	45	19	26	9.774	< 0.05
	II	27	4	23
	III/IV	8	0	8
Clinical stage	G1	21	10	11	6.351	< 0.05
	G3	32	5	27
	G2/G3	27	8	19
Menopause	Yes	41	20	21	0.864	> 0.05
	No	39	15	24
Vascular invasion	≤ 50%	52	7	45	16.953	< 0.05
	> 50%	28	16	12
Lymph node metastasis	Positive	24	1	23	10.115	< 0.05
	Negative	56	22	34

“-” indicates the negative expression of SERPINA3; “+” indicates the positive expression of SERPINA3.