Predictors of dehydration and acute renal failure in patients with diverting loop ileostomy creation after colorectal surgery

Table 3 Univariate and multivariate analysis of clinical factors associated with high-output related complications (dehydration and acute renal failure)

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Index surgery	1.0
Elective
Urgent	2.6 (1.01-8.82)	0.047
Complications after index surgery	3 (1.15-7.97)	0.024
Yes
Ulcerative Colitis	4.8 (1.33-17.75)	0.017	7.6 (1.81-31.95)	0.006
Immunomodulators	5.4 (0.85-34.63)	0.074
Steroids	4.3 (1.42-13.41)	0.010
Biologics (anti-TNF)	7 (0.60-80.85)	0.119
Ileostomy output at discharge ≥ 1000 mL/24 h	3.2 (1.24-8.26)	0.016	3.3 (1.18-9.37)	0.023
Discharge with loperamide	2.8 (1.09-7.24)	0.032
Yes

The reference category has an odds ratio of 1.0. For multivariable backward logistic regression analysis, odds ratio (OR) and 95% confidence interval (CI) are presented, and only significant results are shown.