Female genital tract metastasis of lung adenocarcinoma with EGFR mutations: Report of two cases

Figure 1 Case 1. A: Positron emission tomography-computed tomography (PET-CT) was performed before lung biopsy and showed hyper-metabolic activity in pulmonary lesions and the cervix uteri; B: PET-CT image showed hyper-metabolic activity in the inferior lobe of the right lung, where lung biopsy was performed; C: CT showed a right pulmonary mass characterized by a solid region with contiguous ground-glass areas, stellate borders, and pleural puckering before tyrosine kinase inhibitor treatment; D: CT showed a right pulmonary mass after 2 mo of gefitinib therapy, which indicated partial remission of tumor; E: CT image showed a right pulmonary mass after 4 mo of gefitinib therapy; F: Magnetic resonance imaging performed on April 12, 201 indicated brain metastasis.