Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis

doi:10.12998/wjcc.v7.i12.1367

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jun 26, 2019; 7(12): 1367-1382
Published online Jun 26, 2019. doi: 10.12998/wjcc.v7.i12.1367

Table 1 International guidelines for hepatocellular carcinoma surveillance programs

Guideline	Indications	AFP	Imaging	Period (mo)
WHO	HBV DNA > 2000 UI/mL, HCV cirrhosis	+	US	6
Canadian	Cirrhosis, HBV chronic carriers		US	6
AASLD	Cirrhosis	+/-	US	6
NCCN	Cirrhosis, HBV chronic hepatitis	+/-	US	6
Australian			US
EASL			US	6
Japan	Cirrhosis	+	US/dynamic CT/MRI	3-6
Asia-Pacific		> 200 ng/mL	US	6

AASLD: American Association for the Study of Liver Diseases; CT: Computed tomography; EASL: European Association for the Study of the Liver; HBV: Hepatitis B virus; HCV: Hepatitis C virus; MRI: Magnetic resonance imaging; NCCN: National Comprehensive Cancer Network; US: Ultrasonography; WHO: World Health Organization.

Citation: Balaceanu LA. Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis. World J Clin Cases 2019; 7(12): 1367-1382
URL: https://www.wjgnet.com/2307-8960/full/v7/i12/1367.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i12.1367